Tsunade is a character from the Naruto franchise. She becomes the fifth Hokage (fifth fire shadow) after the death of her teacher, Hiruzen Sarutobi. She is one of the legendary Sannin and is the sole female member in that group. She is a master of Medical Ninjutsu. Her grandfather is Hashirama Senju, The First Hokage. She was originally also a gambler before becoming Hokage and would always lose. She was a teacher to Sakura Haruno and is the sole reason why the latter is what she is today.