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Professor Pippy Pee-Pee Poopypants was a scientist from New Swissland. He is the main antagonist of the novels and one of the two main antagonists (the other being Melvin Sneedly) and the central antagonist of the film. He planned to solve the Earth's hunger and trash problems but then he planned to shrink the entire planet for laughing at his silly name. He failed and was hauled off to jail. He changed his name in a failed attempt to stop other people from making fun of it, which only made things worse. He later escapes from jail to get his revenge on George, Harold and Captain Underpants, but ultimately triggered a chain of event leading up to several major events in the Earth's geological history, as well as his own death three times.

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