Fictional characters who are brothers or sisters of other characters, either hero or villain - this category can also include half-siblings and step-siblings as well as adoptive siblings.
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A
- Aaron Powers
- Abigail (Elmo's World)
- Abigail Lincoln
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- Abraham Simpson
- Ace Hart
- Gomez Addams
- Gomez Addams (Wednesday)
- Great Auntie Sloom
- Morticia Addams
- Pubert Addams
- Pugsley Addams
- Pugsley Addams (Wednesday)
- Wednesday Addams
- Wednesday Addams (Wednesday)
- Addie Singer
- Adella (The Little Mermaid)
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- Ai (Pretty Cure)
- Alana
- Alandra La Forge
- Aldrin Pesky
- Alex (Elmo's World)
- Alex Danvers
- Alex Russo
- Alice Liddell
- Alice Snuffleupagus
- Alix Kubdel
- Alphonse Elric
- Alvin & the Chipmunks (Live-Action Movies)
- Alvin and the Chipmunks
- Alya Césaire
- Amaya (The Dragon Prince)
- Amy (Barney and the Backyard Gang)
- Anais Watterson
- Anakin Solo
- Anastasia Tremaine
- Andrea Harrison
- Andrew Neyman
- Andrina
- Android 18
- Angelina Mouseling
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- Annie (HooplaKidz)
- Annie (Little Einsteins)
- Annoying Orange
- Anti-Pops
- Anton (Once Upon a Time)
- April, May and June Duck
- Aquata
- Archibald Strutter
- Ariel (Disney)
- Arista
- Arthur Read
- Ashley Graves
- Ato
- Attina
- Aubrey Iverson
- Aunt Nanner
- AwesomeAlfonso13
- Azula
B
- Babies (Elmo's World)
- Baby Scooter
- Baby Scrat
- Baby Sinclair
- Bad Bob
- Bailey (Bailey's Book House)
- Balderry
- Banana Cat
- Banana Ladies (Elmo's World)
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- Barley Lightfoot
- Bart Simpson
- Bart West-Allen (Arrowverse)
- Bashful (Once Upon a Time)
- Bathtub
- Bebe Stevens
- Becky Lopez
- Bed and Pillow
- Bella Pesky
- Bellamy Blake
- Ben Greenbloom
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- Bernard (Doraemon)
- Bessie Higgenbottom
- Betsy
- Betty DeVille
- Bibi (Condor Family)
- Big Macintosh
- Blackfire
- Blake Gripling
- Blinky Bill
- Bliss
- Blitzo Buckzo
- Blossom (The Powerpuff Girls 1998)
- Blue (Pokémon)
- Blue Fishes (Elmo's World)
- Bo (Mighty Orbots)
- Bo-Katan Kryze
- Bonnie Rockwaller
- Boo (Mighty Orbots)
- Booker
- Boruto Uzumaki
- Bossk
- Boyfriend (Friday Night Funkin')
- Brianna Buttowski
- Bridget Fitzsimmons
- Brittany Miller
- Brock (Anime)
- Brock (Game) (Pokémon)
- Brooklyn T. Guy
- Brother Bear
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- Bruno Madrigal
- Bryson Williams
- Bubbles (The Powerpuff Girls 1998)
- Bubbles (The Powerpuff Girls 2016)
- Bud (Nina and The Neurons)
- Bulduga
- Bulltaro
- Bulma
- Bundles Snuggle Stuff
- Bunnicula's Brother
- Butch (Droopy)
- Brad Buttowski
- Byakuya Togami
C
- Caitlin Fairchild (DC Comics)
- Cal Stone
- Camilo Madrigal
- Candace Flynn
- Candace Flynn (Star Wars)
- Candy (Glitter Force)
- Cape Riding Hood
- Captain Phasma
- Cara LeJeune
- Carl Foutley
- Carl Grimes
- Carl Johnson
- Carly Shay
- Carol (The Magical Mystery Trip Through Little Red's Head)
- Carrie (Total Drama)
- Carver Descartes
- Cassi
- Cassian Andor
- Celine (Zenonia)
- Cersei Lannister
- Charlie Brown
- Chase (PAW Patrol)
- Chazz Princeton
- Chef Pee Pee’s Sister
- Chen
- Chiko
- Chip and Dale
- Chippo (Animal Planet)
- Chippy
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- Chloé Bourgeois
- Chocolate Banana Girl
- Chris (Nursery Rhyme Street)
- Chris Griffin
- Chris Robinson
- Chrissy Carson
- Chuck Wallace
- Chuckie Finster
- Chunk the Boar
- Cinnamoroll
- Claire Dearing
- Clark (Commander Clark)
- Clawdeen Wolf
- Cleo (Cleo & Cuquin)
- Cleo Lion
- Clifford (We Bare Bears)
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- Clover (Totally Spies)
- Commander Pigo
- Computer and Mouse
- Connor Hawke (Arrowverse)
- Cookie (Animal Crossing)
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- Coral (PAW Patrol)
- Corey Riffin
- Cory Baxter
- Courtney Babcock
- Courtney Gripling
- Cragger
- Craig Williams
- Crash and Eddie
- Cricket Green
- Cupcake (Cupcake & Dino)
- Cuphead
- Curly Bear